Drug-like Properties: Concepts, Structure Design and Methods: from ADME to Toxicity Optimization,   ISBN:9780123695208

Customer Rating: 

This book contains a wealth of information concerning a number of topics of special interest to medicinal chemists in the pharmaceutical or animal science business. On many occasions I have sought and found useful information in this book - it serves as a very good primary source for basic information related to many aspects of preclinical drug discovery. This book fills a great void and should find its way onto the desk of any medicinal chemist who wants to learn more about understanding and manipulating the pharmaceutical properties of their compounds. Highly recommended!!

Customer Rating: 

It is very nice overview of the practical topics for the practicing medicinal chemist.
For the just arrived synthetic chemist, it represents a way of looking not so puzzled in project meetings when interacting with experienced collegues.
For senior drug-hunters, it is a guide to check for clear understanding of drug properties in the selection and optimization of new leads. Emphasis is placed on the methods for measuring properties using high throughput, diagnostic and in-depth methods.
In a nutshell, a very useful learning material for scientists engaged in drug discovery and a reference for regular use.

Customer Rating: 

I needed to know what makes a good orally active drug. This book gave me most of the answers I needed in a very short amount of time. It's well written, well organized, and not too dense with jargon. There's a lot of overlap between chapters, which is good for quick reference but would probably bore a more informed reader.

Customer Rating: 

I have spent some of the last two days reading this book and I am very impressed with it. It is destined to become an authoritative text on the whole topic area of drug-like molecules and ADME screening. The chapters are well written and include sufficient detail and references so that the reader can make use of the information effectively. The book could be used in a graduate-level course for medicinal chemists or DMPK scientists.
The book would also be very helpful for scientists working in one area of DMPK who wish to become DMPK project managers and need to increase their understanding of other areas of DMPK that are outside of their own specific expetise function. The chapter on pharmacokinetics was well written and provides a very good overview of the topic. Overall, I can state that this book is well worth the purchase price.