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Bioconjugate Techniques, Second Edition,   ISBN:9780123705013

     
  Bioconjugate Techniques, Second Edition

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Binding: Hardcover
Release Date: May 2008
Edition: 2
List Price: $99.95

Average Customer Rating:
Score = 4.5 Score = 4.5 Score = 4.5 Score = 4.5 Score = 4.5

ISBN-13: 9780123705013
ISBN-10: 0123705010
Author: Greg T. Hermanson
Publisher: Academic Press
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Summaries and Customer Reviews are supplied by Amazon.com

Summary:

Bioconjugate Techniques, 2e provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers.

*A one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab, allowing for fast retrieval of tried and tested techniques for synthesizing bioconjugates.

*Step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates.

*Includes more than 600 figures that visually describe the complex reactions associated with the synthesis of bioconjugates, giving researchers a better understanding of how the commercially available reagents facilitate the crosslinking of peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers.

*Includes entirely new chapters on the latest areas in the field of bioconjugation as follows:
Microparticles and nanoparticles
Silane coupling agents
Dendrimers and dendrons
Chemoselective ligation
Quantum dots
Lanthanide chelates
Cyanine dyes
Discrete PEG compounds
Buckyballs, fullerenes, and carbon nanotubes
Mass tags and isotope tags
Bioconjugation in the study of protein interactions

Customer Reviews:

Average Customer Rating: Score = 4.5 Score = 4.5 Score = 4.5 Score = 4.5 Score = 4.5

lots of details
Customer Rating:  Score = 3 Score = 3 Score = 3 Score = 3 Score = 3

There are a lot of details in this textbook. For chemistry majors, it might be preferable but for engineering students, it is a disaster.

You need this book to modify proteins
Customer Rating:  Score = 5 Score = 5 Score = 5 Score = 5 Score = 5

It's an excellent reference to those practice conjugation of proteins and nucleic acids. It provides detail experiment conditions and tips to set up the experiment correctly and successfully.

A must-have, comprehensive reference book that will empower you to build anything biologically relevant!
Customer Rating:  Score = 5 Score = 5 Score = 5 Score = 5 Score = 5

This book is not one that's meant to be read from cover to cover. For the academic seeking to build a molecule or put together particulate systems, conjugate proteins onto some sort of substrate, modify surfaces to produce certain biologically active moieties, etc., this book is a must-have reference that contains:
- Clear explanation of what kind of chemistry is involved
- Concise, easy to follow outline of reaction conditions that must be kept in mind.
- Good figures and diagrams of the reactions of interest
- Well-researched protocols that serve as a point of reference for your experimental plans.

This edition is a significant upgrade from the previous edition, with newly written chapters on microspheres and quantum dots, among some. Whenever I need help figuring out how to attach certain biomolecules to various surfaces in my research, this is my go-to book, and I have seen plenty of labs in my area that have at least one copy of this book on the shelf.

Overall, probably too heavy to read from cover to cover, but makes for an awesome desk reference for grad students and researchers in biologicalk and biotech-related disciplines.

Fantastic, easy to read book
Customer Rating:  Score = 5 Score = 5 Score = 5 Score = 5 Score = 5

I am always extremely leary of biochemistry and/or bioconjugate books because if you're looking for a specific answer, you're not going to find it in a book. Instead, you have to bother those with experience and learn from their techniques. HOWEVER, this book is an exception in the highest regard! I was able to easily derive a surface chemistry protocol in around 10 minutes, and it only took me that long because I was fascinated on how direct this book was. Basically here's what you get:
1) Easy to read/decipher information
2) Fantastic Index
3) Quick answers that I couldn't even find on Google

Best of all, in my opinion, is that each section is not prefaced with the past history of who/what/where/when/why, which although sometimes interesting, gives you no assistance in the lab.

a good book in bioconjugate chemistry area
Customer Rating:  Score = 4 Score = 4 Score = 4 Score = 4 Score = 4

It is hard for a chemistry major student to switch to biochemistry area. When a chem student try to read the big biochemistry textbook, he will be dizzy because of so many reaction equations and biocircles. To his most surprise, those equations are quite different with what he learned in origanic lecture. What shall he begin to go into the new world? Read Bioconjugate Technique --- this book will give Refresh you!

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